Title of article
Alkynes to (E)-enolates using tandem catalysis: stereoselective anti-aldol and syn-[3,3]-rearrangement reactions
Author/Authors
Neil P. Grimster، نويسنده , , Donna A.A. Wilton، نويسنده , , Louis K.M. Chan، نويسنده , , Christopher R.A Godfrey، نويسنده , , Clive Green، نويسنده , , Dafydd R. Owen، نويسنده , , Matthew J. Gaunt، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
8
From page
6429
To page
6436
Abstract
A new tandem catalysis strategy that transforms alkyne derivatives to (E)-enol-equivalents followed by stereoselective anti-selective aldol coupling or syn-selective [3,3]-rearrangement transformations is reported. The mechanism is thought to proceed through an interchanging series of Lewis acid and Brønsted acid catalyzed reactions via the intermediacy of a ketiminum ion species.
Keywords
Stereoselective aldol , enolate , Stereoselective Sigmatropic rearrangement , alkyne , Tandem catalysis
Journal title
Tetrahedron
Serial Year
2010
Journal title
Tetrahedron
Record number
1101160
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