Title of article :
A synthesis of (−)-ebelactones A and B
Author/Authors :
John P. Cooksey، نويسنده , , Rhonan Ford، نويسنده , , Philip J. Kocienski، نويسنده , , Béatrice Pelotier، نويسنده , , Jean-Marc Pons، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
A synthesis of the β-lactone esterase inhibitors (−)-ebelactones A and B is described. The synthesis features the use of a Hoppe homoaldol reaction and a Cu(I)-mediated 1,2-metallate rearrangement of a metallated enol carbamate as key fragment linkage reactions.
Keywords :
1 , Ebelactone B , Roush crotylmetallation , Ebelactone A , 2-Metallate rearrangement , Hoppe homoaldol reaction
Journal title :
Tetrahedron
Journal title :
Tetrahedron
