Title of article :
Synthesis of pyrimido[6,1-a]isoquinolines via a one-pot, four-component reaction
Author/Authors :
Abdolali Alizadeh، نويسنده , , Atieh Rezvanian، نويسنده , , Log-Guan Zhu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
An efficient one-pot synthesis of pyrimido[6,1-a]isoquinoline-1-carboxylate derivatives is described. This involves the four-component reaction between primary amines, alkyl acetoacetates, isoquinoline and trichloromethylchloroformate (diphosgene) under mild conditions at ambient temperature.
Keywords :
Trichloromethylchloroformate , Alkyl acetoacetates , enaminone , Pyrimido-isoquinoline , Four-component reaction
Journal title :
Tetrahedron
Journal title :
Tetrahedron
