Author/Authors :
Marie Devert، نويسنده , , Cyrille Sabot، نويسنده , , Pascale Giboreau، نويسنده , , Jean-François Constant، نويسنده , , Andrew E. Greene، نويسنده , , Alice Kanazawa، نويسنده ,
Abstract :
The first total synthesis of (±)-17-norcamptothecin, a novel camptothecin analog possessing an α-hydroxy-γ-lactone E-ring, has been accomplished by using a short and flexible route. The stability of this new compound in aqueous medium has been evaluated through fluorescence spectroscopy.
