Author/Authors :
Ana L?cia Cardoso، نويسنده , , Ana Matos Beja، نويسنده , , Manuela Ramos Silva، نويسنده , , Jes?s M. de los Santos، نويسنده , , Francisco Palacios، نويسنده , , Paulo E. Abreu، نويسنده , , Alberto A.C.C. Pais، نويسنده , , Teresa M.V.D. Pinho e Melo، نويسنده ,
Abstract :
Stereoselective inverse conjugate addition of carbonucleophiles to allenoates bearing a chiral auxiliary in the ester moiety afforded optically active α,β-unsaturated carboxylic esters bearing a new stereocenter at the δ position. The rationalization of the observed selectivity was supported by semi-empirical molecular orbital calculations.
Keywords :
Chiral ? , ?-unsaturated carboxylic esters , Chiral carbon centers , Stereoselective inverse conjugate addition , Allenoates , Carbonucleophiles
