Title of article
Facile Cu-free Sonogashira cross-coupling of nucleoside C-6 arylsulfonates with terminal alkynes
Author/Authors
Felix N. Ngassa، نويسنده , , Jamie M. Gomez، نويسنده , , Brandon E. Haines، نويسنده , , Michael J. Ostach، نويسنده , , Jared W. Hector، نويسنده , , Lindsay J. Hoogenboom، نويسنده , , Chelsea E. Page، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2010
Pages
8
From page
7919
To page
7926
Abstract
The combination of PdCl2[CH3CN]2 with XPhos is an efficient catalytic system for the Sonogashira-type cross-coupling of 2′-deoxyguanosine O6-arylsulfonates with terminal alkynes. The reactions generally proceed under mild conditions requiring no Cu co-catalyst to give the corresponding C-6-alkynylated deoxynucleosides in moderate to good yields.
Journal title
Tetrahedron
Serial Year
2010
Journal title
Tetrahedron
Record number
1101329
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