Title of article
An Efficient Synthesis of 2,3-Aziridino-(gamma)-lactones from Azetidin-2-ones
Author/Authors
Kale، Ajaykumar S. نويسنده , , Deshmukh، Abdul Rakeeb A. S. نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-236
From page
237
To page
0
Abstract
An efficient synthesis of enantiopure 2,3-aziridino-(gamma)-lactones from azetidin-2-ones is described. Acid-catalyzed tandem intramolecular azetidinone ring opening followed by aziridine ring formation via elimination of a mesylate group is the key step in this synthesis. 2.3-Aziridino-(gamma)-lactones are important precursors for biologically important glutamic acid derivatives.
Keywords
azetidin-2-ones , glutamic acid , lactones , aziridines
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110234
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