Title of article
Towards the Synthesis of Paulitin: New Insights into the Enyne-Metathesis Mechanism
Author/Authors
Kaim، Laurent El نويسنده , , Grimaud، Laurence نويسنده , , Vedrenne، Emeline نويسنده , , Royer، Frederique نويسنده , , Oble، Julie نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-2378
From page
2379
To page
0
Abstract
In our approach towards Paulitin, a sesquiterpene lactone, we have shown that steric hindrance at the propargylic position is of importance to the outcome of enyne metathesis. Moreover, we have uncovered further evidence to confirm that the alkyne-first pathway should be the favored process in enyne metathesis.
Keywords
Alkyne , metathesis , steric hindrance , 1,3-dienes , Mechanism
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110237
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