Author/Authors :
Keiji Fushimi، نويسنده , , Madoka Horikawa، نويسنده , , Kaori Suzuki، نويسنده , , Atsushi Sekiya، نويسنده , , Susumu Kanno، نويسنده , , Susumu Shimura، نويسنده , , Hirokazu Kawagishi، نويسنده ,
Abstract :
Five novel compounds, applanatines A–E (1–5), and a known one (6) were isolated from the culture broth of Ganoderma applanatum. Their structures including the relative configurations were determined by the interpretation of spectroscopic data. Compounds 3 and 4 suppressed the growth of Fusobacterium nucleatum, that is, a prominent member of the oral microflora implicated in periodontitis.
