Title of article :
Synthesis of nitrogen bicyclic scaffolds: pyrimido[1,2-a]pyrimidine-2,6-diones
Author/Authors :
Sylvain Grosjean، نويسنده , , Smail Triki، نويسنده , , Jean Claude Meslin، نويسنده , , Karine Julienne، نويسنده , , David Deniaud، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2010
Abstract :
The multi-step synthesis of 1,3,7-trisubstituted pyrimido[1,2-a]pyrimidinediones starting from isothiocyanates is described. These nitrogen bicycles were prepared by an iterative sequence of functionalization/cyclocondensation reactions. [4+2] Cycloaddition reactions took place between diazadienic chains and various acyl chlorides providing sophisticated heterobicycles.
Keywords :
3-diazabutadienes , 1 , Methylsulfanyl group , Nitrogen heterocycles , Dihydropyrimidinones
Journal title :
Tetrahedron
Journal title :
Tetrahedron
