• Title of article

    Synthesis of the AC Ring of Paclitaxel: Formation of the C Ring by [3+2] Cycloaddition with a Preformed A Ring

  • Author/Authors

    Takahashi، Takashi نويسنده , , Doi، Takayuki نويسنده , , Nakai، Kazuoki نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    -865
  • From page
    866
  • To page
    0
  • Abstract
    The stereoselective formation of the C ring was accomplished by nitrile oxide [3+2] cycloaddition of an intermediate with the A ring already constructed. We found that stereoelectronic effect to a 1,1-substituted alkene moiety is important in the reaction.
  • Keywords
    Paclitaxel , nitrile oxide , Cycloadditions
  • Journal title
    Synlett
  • Serial Year
    2005
  • Journal title
    Synlett
  • Record number

    110280