Title of article
Aza variant of intramolecular nucleophile-catalyzed aldol lactonization (NCAL): formal synthesis of (3S,4R) and (3R,4S) 4-(hydroxymethyl)pyrrolidin-3-ol
Author/Authors
Dimpy Sikriwal، نويسنده , , Dinesh K. Dikshit، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
6
From page
210
To page
215
Abstract
Aza variant of intramolecular catalytic, asymmetric nucleophile-catalyzed, aldol lactonization (NCAL) reaction has been explored to synthesize β-lactone fused nitrogen heterocycles as aza sugars’ precursors by employing achiral amino acids. The utility of these bicyclic β-lactones is presented by the formal synthesis of aza sugars, (3S,4R) and (3R,4S) 4-(hydroxymethyl)pyrrolidin-3-ol.
Keywords
Aza sugars , Aza-NCAL reaction , ?-Lactone , O-Acetylquinidine , O-Acetylquinine
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1102816
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