Title of article :
FeCl3·6H2O-promoted skeleton-rearrangement of 1-substituted-3-benzazepines: substrate extension and product utilization
Author/Authors :
Jing Zhang، نويسنده , , Kui Wu، نويسنده , , Meining Wang، نويسنده , , Jianqin Jiang، نويسنده , , Ao Zhang، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
FeCl3·6H2O-promoted skeleton-rearrangement of 1-substituted-3-benzazepines was further exploited. Both 1-aryl- and 1-alkyl- or 1-alkenyl-benzazepines underwent this reaction smoothly. The rearrangement products were used to prepare a series of novel derivatives containing both tetrahydroisoquinoline (THIQ) and tetrahydropyrimidin-4(1H)-one scaffolds through a Mannich-type process.
Keywords :
tetrahydroisoquinoline , 1-Substituted benzazepine , Ring arrangement , Iron (III) chloride , Tetrahydropyrimidin-4(1H)-one
Journal title :
Tetrahedron
Journal title :
Tetrahedron
