Title of article
A rapid and convenient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2-ones and thiones
Author/Authors
Zhanxiong Fang، نويسنده , , Yulin Lam، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
1294
To page
1297
Abstract
A rapid and convenient synthesis of 5-unsubstituted 3,4-dihydropyrimidin-2-ones and thiones was developed. The reaction involves a one-pot reaction between oxalacetic acid, thiourea/urea, and aldehyde under microwave irradiation and provides the products in good yields and much shorter reaction times.
Keywords
Microwave reaction , Biginelli reaction , multicomponent reaction , Chemoselectivity , Cyclocondensation
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1102952
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