Title of article :
Library construction of 1-(1H-imidazol-1-yl)-1,2-dihydroisoquinolines via three-component reaction of 2-alkynylbenzaldehyde, amine, and imidazole
Author/Authors :
Honglei Lou، نويسنده , , Shengqing Ye، نويسنده , , Jianfeng Zhang and Charles Dalton، نويسنده , , Jie Wu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Parallel diversity-oriented synthesis of diverse 1-(1H-imidazol-1-yl)-1,2-dihydroisoquinolines via AgOTf-catalyzed three-component reaction of 2-alkynylbenzaldehyde, amine, and imidazole is described. This reaction works efficiently under mild conditions to generate a small library of imidazole-incorporated 1,2-dihydroisoquinolines.
Keywords :
Imidazole , 2-Dihydroisoquinoline , silver triflate , Amine , 1-(1H-Imidazol-1-yl)-1 , 2-Alkynylbenzaldehyde
Journal title :
Tetrahedron
Journal title :
Tetrahedron
