Title of article
Synthesis and biological evaluation of aziridine-containing analogs of phytosphingosine
Author/Authors
Stéphanie Ballereau، نويسنده , , Nathalie Andrieu-Abadie، نويسنده , , Nathalie Saffon، نويسنده , , Yves Génisson، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
9
From page
2570
To page
2578
Abstract
Six new aziridine-containing analogs of phytosphingosine designed as constrained anhydrophytosphingosine were synthesized. The synthetic route developed also afforded an access to an original bicyclic analog of the natural anhydrophytosphingosine jaspine B. All these new compounds were evaluated for their capacities to affect melanoma cell viability.
Keywords
Phytosphingosine , Sphingosine , Aziridine , Jaspine B , Ceramide
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103090
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