Single-Step Stereoselective Synthesis of (E)- and (Z)-Allylamines from Acetyl Derivatives of Baylis-Hillman Adducts

Stereoselective synthesis of (E)- and (Z)-allylamines has been achieved in a single-step by treatment of the acetyl derivatives of Baylis-Hillman adducts with ammonium acetate in anhydrous methanol at room temperature. The reaction proceeded under neutral conditions to form the corresponding allylamines in high yields and stereoselectivity.