Title of article :
Stereoselective total synthesis of (−)-cleistenolide
Author/Authors :
Dokuburra Chanti Babu، نويسنده , , Jondoss Jon Paul Selavam، نويسنده , , Dorigondla Kumar Reddy، نويسنده , , Vanam Shekhar، نويسنده , , Yenamandra Venkateswarlu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
A stereoselective total synthesis of (−)-cleistenolide (1) derived from d-(−)-isoascorbic acid has been described. The new synthetic strategy involves highly diastereoselective reduction, one-pot protection of required benzoyl, acetyl groups, and the RCM reaction by using Grubbs catalyst are the key steps with considerable yields.
Keywords :
(?)-Cleistenolide , Cleistochlamys kirkii , K-Selectride , Oxa-Micheal addition , d-(?)-Isoascorbic acid , Grubbs RCM
Journal title :
Tetrahedron
Journal title :
Tetrahedron
