Author/Authors :
Jian-Hong Yang، نويسنده , , Hai-Yan Zhang، نويسنده , , Xue Du، نويسنده , , Wei Wang، نويسنده , , Wei-Lie Xiao، نويسنده , , Jin Wen، نويسنده , , Jian-Xin Pu، نويسنده , , Xican Tang، نويسنده , , Han-Dong Sun، نويسنده ,
Abstract :
Fourteen new dibenzocyclooctadiene lignans, ananonins A–N (1–14), together with five known compounds, were isolated from the seeds of Kadsura ananosma. The structures and absolute configurations of 1–14 were established using a combination of MS, NMR, and CD techniques. The biological activity of these compounds was evaluated, and ananonin M (13) showed moderate neuroprotective effects in an in vitro assay.
Keywords :
Kadsura ananosma , Dibenzocyclooctadiene lignans , Ananonins , Neuroprotective effect
