Title of article :
A convenient route to functionalized 3-amino-N-methylfuro[3,2-b]pyridine-2-carboxamides
Author/Authors :
Anne Bretéché، نويسنده , , Pascal Marchand، نويسنده , , Marie-Renée Nourrisson، نويسنده , , Patrick Hautefaye، نويسنده , , Guillaume De Nanteuil، نويسنده , , Muriel Duflos، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
The synthesis of novel functionalized 3-amino-N-methylfuro[3,2-b]pyridine-2-carboxamides is described from cyanopyridine intermediates. Based on the difference in halogen reactivity, ethyl [(5-bromo-2-chloropyridin-3-yl)oxy]acetate was functionalized by a palladium-catalyzed reaction, before the cyclization to the desired furo[3,2-b]pyridines.
Keywords :
2-b]pyridine-2-carboxylates , 2-b]pyridine-2-carboxamides , heteroannulation , 2-b]pyridines
Journal title :
Tetrahedron
Journal title :
Tetrahedron
