Title of article :
FeCl3·6H2O-catalyzed synthesis of substituted cis-2,6-tetrahydropyrans from ζ-hydroxy allylic derivatives
Author/Authors :
Amandine Guérinot، نويسنده , , Anna Serra-Muns، نويسنده , , Charlélie Bensoussan، نويسنده , , Sébastien Reymond، نويسنده , , Janine Cossy، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
A highly diastereoselective iron-catalyzed synthesis of substituted cis-2,6-tetrahydropyrans from ζ-hydroxy allylic derivatives is described. The FeCl3·6H2O-induced epimerization of the formed 2-alkenyl 6-substituted tetrahydropyrans is the key reaction to account for the high diastereoselectivities observed.
Keywords :
Iron trichloride , Tetrahydropyran , Epimerization , Diastereoselectivity , Heterocyclization
Journal title :
Tetrahedron
Journal title :
Tetrahedron
