• Title of article

    Application of the Radical Cascade of Acyclic Peptide-Based Precursors into Analogues of Type I (beta)-Turn

  • Author/Authors

    Cmoch، Piotr نويسنده , , Stalinski، Krzysztof نويسنده , , Stepien، Anita نويسنده , , Loska، Rafal نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    -82
  • From page
    83
  • To page
    0
  • Abstract
    Radical cyclizations of di-, tri- and tetrapeptides containing N-2-bromobenzyl,N-methyl-substituted alanine or aspartic acid lead in good yields to (alpha),(beta)-unsaturated (gamma)-lactams. The overall cascade, relying on a hydrogen atom transfer-elimination strategy could serve as a way to incorporate a flat and rigid five-membered ring into the peptide framework.
  • Keywords
    domino reactions , peptides , protecting groups , Radicals , ring constructions
  • Journal title
    Synlett
  • Serial Year
    2005
  • Journal title
    Synlett
  • Record number

    110344

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=110344