Title of article :
Tandem intramolecular oxa-Michael addition/decarboxylation reaction catalyzed by bifunctional cinchona alkaloids: facile synthesis of chiral flavanone derivatives
Author/Authors :
Haifeng Wang ، نويسنده , , Hua Xiao، نويسنده , , Xiao-Wei Wang، نويسنده , , Gang Zhao، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2011
Abstract :
Bifunctional cinchona alkaloids were used to catalyze a tandem intramolecular oxa-Michael addition/decarboxylation reaction of alkylidene β-ketoesters 1, providing a series of flavanone derivatives with up to 97% yield and 93% ee.
Keywords :
Oxa-Michael Addition , Decarboxylation , Enantioselectivity , Bifunctional cinchona alkaloids , Flavanones
Journal title :
Tetrahedron
Journal title :
Tetrahedron
