Title of article :
A Facile Regioselective Decomposition of Tosylhydrazones: An Application towards the Synthesis of (alpha)-Lipoic Acid
Author/Authors :
Chavan، Subhash P. نويسنده , , Kale، Ramesh R. نويسنده , , Pasupathy، K. نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
A facile regioselective decomposition of tosylhydrazones using NaOH as a base in refluxing isopropyl alcohol is described. This finding has been successfully applied towards the synthesis of (+-)-(alpha)-lipoic acid (1).
Keywords :
regioselectivity , Olefins , (alpha)-lipoic acid , tosylhydrazones