Title of article
Direct asymmetric aldol reactions in brine with recyclable fluorous β-aminosulfonamide organocatalysts
Author/Authors
Tsuyoshi Miura، نويسنده , , Kie Imai، نويسنده , , Hikaru Kasuga، نويسنده , , Mariko Ina، نويسنده , , Norihiro Tada، نويسنده , , Nobuyuki Imai، نويسنده , , Akichika Itoh، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
7
From page
6340
To page
6346
Abstract
Fluorous organocatalyst 3 promotes direct asymmetric aldol reactions of ketones with aldehydes in brine, leading to the synthesis of the corresponding anti-aldol products in high yields with up to 96% ee. Fluorous organocatalyst 3 is easily recovered by solid-phase extraction using fluorous silica gel and can be reused up to five times without purification.
Keywords
Organocatalyst , Aldol , Water , Recycle , Fluorous
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103563
Link To Document