Title of article
The reaction of optically active α-aminocarboxylic acid hydrazides with triethyl orthoesters
Author/Authors
Agnieszka Kudelko، نويسنده , , Wojciech Zieli?ski، نويسنده , , Krzysztof Ejsmont، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
8
From page
7838
To page
7845
Abstract
New derivatives of 2-(1-amino-1-phenylmethyl)-1,3,4-oxadiazole and 1,2,4-triazin-6-one were synthesised in the reactions of optically active α-aminocarboxylic acid hydrazides and triethyl orthoesters in xylene. The electronic and steric effects of substituents at the α position influencing the formation of five- or six-membered products are discussed.
Keywords
Lanthanide shift reagent , 4-Triazin-6-one , 2 , ?-Aminocarboxylic acid hydrazide , racemisation , 2-Aminomethyl-1 , 3 , pKa Ionisation constant , 1 , 4-oxadiazole , Synthesis
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103729
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