Title of article
Expedient synthesis of 4-O-methylhonokiol via Suzuki–Miyaura cross-coupling
Author/Authors
Jae-Hwan Kwak، نويسنده , , Young Ae Cho، نويسنده , , Jae-Yong Jang، نويسنده , , Seung-Yong Seo، نويسنده , , Heesoon Lee، نويسنده , , Jin Tae Hong، نويسنده , , Sang-Bae Han، نويسنده , , Kiho Lee، نويسنده , , Young-Shin Kwak، نويسنده , , Jae-Kyung Jung، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
4
From page
9401
To page
9404
Abstract
Concise and practical synthesis of 4-O-methylhonokiol was achieved in 34% overall yield. The key features of our synthesis include chemoselective ortho-mono bromination of phenol as well as biaryl formation via Suzuki–Miyaura cross-coupling, in which bromophenol was reacted with potassium aryltrifluoroborate using Pd(OAc)2 and RuPhos under microwave conditions.
Keywords
Potassium aryltrifluoroborate , Neolignan , Suzuki–Miyaura cross-coupling , 4-O-Methylhonokiol
Journal title
Tetrahedron
Serial Year
2011
Journal title
Tetrahedron
Record number
1103910
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