Title of article :
Polymer-Supported (beta)-Amino Thioesters as Catalysts for the Enantioselective Addition of Diethylzinc to Aldehydes
Author/Authors :
Eriksen، Heidi S. نويسنده , , Oyaga، Sandra Cotes نويسنده , , Sherrington، David C. نويسنده , , Gibson، Colin L. نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
A series of novel polymer-supported thioesters were prepared and found to be effective catalysts for the enantioselective addition of diethylzinc to benzaldehyde. These catalysts gave 1-phenylpropanol in up to 86% ee. The catalysts were fully recyclable and could be used in subsequent additions with retention of the enantioselectivity and efficiency levels.
Keywords :
Nucleophilic additions , Ligands , Asymmetric catalysis , supported catalysis , Polymers
