Title of article :
Formal synthesis of TMC-69-6H via a one-pot enantioselective domino proline-mediated aldol/olefin homologation procedure
Author/Authors :
Sophie Vuong، نويسنده , , Nicolas Brondel، نويسنده , , Christophe Len، نويسنده , , Sébastien Papot، نويسنده , , Brigitte Renoux، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
Enantioselective synthesis of TMC-69-6H was accomplished from readily accessible pyridone derivative via a domino proline-mediated aldol reaction/olefin homologation, followed by tandem ring-closing and cross metathesis.
Keywords :
Aldolization , proline , Tebbe , Enantioselectivity , Crotylation
Journal title :
Tetrahedron
Journal title :
Tetrahedron
