Title of article :
Stereoselective Synthesis of (beta)-Branched Baylis-Hillman Adducts via Organozinc Species
Author/Authors :
HE، LIN نويسنده , , Guo، Qing-Xiang نويسنده , , Xue، Song نويسنده , , Han، Kai-Zhen نويسنده , , Liu، Yong-Kang نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
An efficient one-pot, three-component coupling reaction for the synthesis of unusual (beta)-branched Baylis-Hillman adducts has been developed. Organozinc species CF3CO2ZnEt added to (alpha),(beta)-acetylenic ketones in a 1,4fashion to yield allenolates, which reacted with aldehydes providing highly functionalized trisubstituted olefins in good to excellent yields with stereoselectivity.
Keywords :
Aldehydes , acetylenic ketones , organozinc species , Baylis-Hillman adducts
