Title of article :
Total synthesis of 2-(2-hydroxyalkyl)-piperidine alkaloids (−)-halosaline and (−)-8-epi-halosaline via iterative asymmetric allylation/RCM strategy
Author/Authors :
Palakodety Radha Krishna، نويسنده , , Bonepally Karunakar Reddy، نويسنده , , Palabindela Srinivas، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
Total synthesis of 2-(2-hydroxyalkyl)-piperidine alkaloids, (−)-halosaline and (−)-8-epi-halosaline is reported from n-butyraldehyde using iterative asymmetric allylation, nucleophilic substitution with an azide and ring-closing metathesis as the key reactions.
Keywords :
Piperidine alkaloids , 2-(2-Hydroxy substituted)-piperidines , Iterative asymmetric allylation , Ring-closing metathesis (RCM)
Journal title :
Tetrahedron
Journal title :
Tetrahedron
