Author/Authors :
Konstantin N. Gavrilov، نويسنده , , Sergey V. Zheglov، نويسنده , , Mariya N. Gavrilova، نويسنده , , Ivan M. Novikov، نويسنده , , Marina G. Maksimova، نويسنده , , Nikolay N. Groshkin، نويسنده , , Eugenie A. Rastorguev، نويسنده , , Vadim A. Davankov، نويسنده ,
Abstract :
Novel P-monodentate phosphite-type ligands have been synthesized in one step from BINOL mono-tosylate and BINOL mono-(−)-menthylcarbonate. The use of these ligands provides up to 96% ee in Pd-catalyzed asymmetric allylic substitution of (E)-1,3-diphenylallyl acetate and up to 99% ee in Rh-catalyzed asymmetric addition of phenylboronic acid to cyclohex-2-enone. The influence of the structural modules such as the nature of phosphorus-containing ring or exocyclic substituent on the enantioselectivity is discussed.
Keywords :
Asymmetric allylic substitution , Palladium , asymmetric addition , Diamidophosphites , Rhodium , Phosphites
