Title of article
Stereocontrolled synthesis of (S)-9-cis-4-oxo-13,14-dihydroretinoic acid
Author/Authors
Marta Dom?nguez، نويسنده , , Susana Alvarez، نويسنده , , Rosana Alvarez، نويسنده , , Angel R. de Lera، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
6
From page
1756
To page
1761
Abstract
(S)-9-cis-4-Oxo-13,14-dihydroretinoic acid (S)-1, a new major endogenous vitamin A metabolite that activates retinoic acid receptor signaling both in vitro and in vivo, has been synthesized stereoselectively by Horner–Wadsworth–Emmons condensation and Stille cross-coupling as bond forming reactions.
Keywords
Retinoids , Stille reaction , Total synthesis , Vitamin A , polyenes
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104219
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