Title of article
An efficient and highly stereoselective synthesis of novel trifluoromethylated trans-dihydrofuro[2,3-c]pyrazoles using arsonium ylides
Author/Authors
Jiaping Zhang، نويسنده , , Shuxin Yang، نويسنده , , Kai Zhang، نويسنده , , Jie Chen، نويسنده , , Hongmei Deng، نويسنده , , Min Shao، نويسنده , , Hui Zhang، نويسنده , , Weiguo Cao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
7
From page
2121
To page
2127
Abstract
An efficient approach of highly stereoselective synthesis of novel trifluoromethylated trans-4,5-dihydrofuro[2,3-c]pyrazoles has been described. Arsonium bromides 1 reacted smoothly with the electron-deficient alkenes (Z)-4-aryl-1-phenyl-3-(trifluoromethyl)-1H-pyrozol-5(4H)-ones 2 to give products trans-dihydrofuro[2,3-c]pyrazoles 3 with high stereoselectivity and in good to excellent yields, using CH2Cl2 as solvent and K2CO3 as base.
Keywords
3-c]pyrazoles , Trifluoromethylated , Stereoselective synthesis , Electron-deficient alkenes , Arsonium ylides
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104261
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