An efficient three-component synthesis of new barbiturate salts

An efficient synthesis of new barbiturate salts consist of 2-aminopyridinium moiety by a‎n uncatalyzed three-component condensation reaction of C–H acids, pyrimidine-tetraones, and 2-aminopyridines‎ in refluxing chloroform is reported. The reaction of pyrimidine-tetraones and 2-aminopyridines with ninhydrin in the formation of new barbiturate salts consist of 2-aminopyridinium moiety is also investigated.