Author/Authors :
Yuji Tanaka، نويسنده , , Asami Sakamoto، نويسنده , , Takanobu Inoue، نويسنده , , Takeshi Yamada، نويسنده , , Takashi Kikuchi، نويسنده , , Tetsuya Kajimoto، نويسنده , , Osamu Muraoka، نويسنده , , Akira Sato، نويسنده , , Yusuke Wataya، نويسنده , , Hye Sook Kim، نويسنده , , Reiko Tanaka، نويسنده ,
Abstract :
Three new gedunins, an andirobin, three mexicanolides, and two phragmalin-type limonoids named andirolides H (1), I (2), J (3), K (4), L (5), M (6), N (7), O (8), and P (9) were isolated from an oil of the flower of Carapa guianensis Aublet (Meliaceae). Their structures including the absolute configurations were determined by means of the NMR and CD spectra as well as FABMS. Andirolide H (1) showed antimalarial activity against Plasmodium falciparum in vitro.
