Title of article
Molecular Iodine-Catalyzed Imine Activation for Three-Component Nucleophilic Addition Reactions
Author/Authors
Janda، Kim D. نويسنده , , Lee، Byoung Se نويسنده , , Mahajan، Suresh نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-1324
From page
1325
To page
0
Abstract
(beta)-Amino ketones and (alpha)-amino nitriles were synthesized from silyl enol ethers and trimethylsilyl cyanides, via a three-component nucleophilic addition reaction with aromatic aldehydes and amines; the reaction was found to be significantly accelerated by molecular iodine under neutral conditions.
Keywords
molecular iodine , three-component reaction , Mannich-type reaction , Strecker-type reaction , imine activation
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110445
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