Title of article
New Simple Chiral Phosphine Oxazolidine Ligands: Easy Synthesis and Application in the Palladium-Catalyzed Asymmetric Allylic Alkylation
Author/Authors
Braga، Antonio L. نويسنده , , Ludtke، Diogo S. نويسنده , , Zeni، Gilson نويسنده , , Sehnem، Jasquer A. نويسنده , , Silveira، Claudio C. نويسنده , , Marchi، Miriam I. نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-1330
From page
1331
To page
0
Abstract
New types of chiral phosphine-oxazolidines have been easily synthesized in a straightforward one-pot process starting from optically active aminoalcohols. They were screened in the Pd-catalyzed asymmetric allylic alkylations of 1,3-diphenyl-2-propenyl acetate with dimethylmalonate. The reaction proceeds smoothly in good to excellent yields and excellent stereoselectivity was obtained (up to 97%).
Keywords
phosphines , oxazolidines , allylic alkylations
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110449
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