Author/Authors :
Kenichi Yamada، نويسنده , , Yasumasa Matsumoto، نويسنده , , Khalid B. Selim، نويسنده , , Yasutomo Yamamoto، نويسنده , , Kiyoshi Tomioka، نويسنده ,
Abstract :
Steric tuning of C2-symmetric chiral N-heterocyclic carbene (NHC) was performed in Au(I)-catalyzed asymmetric cyclization of 1,6-enyne. Higher enantioselectivity was realized when chiral NHC–AuCl/AgSbF6 catalysts whose N-substituent on the NHC overlays the Au–Cl bond was utilized.
