Title of article :
Synthesis of spirofuranopyrimidine–piperidines
Author/Authors :
Etzer Darout، نويسنده , , Kim F. McClure، نويسنده , , Vincent Mascitti، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
A concise synthesis of spirofuranopyrimidines is described and relies on the addition of isopropyl 4-oxopiperidine-1-carboxylate to a pyrimidine dianion. The diol intermediate formed is subjected to cycloetherification conditions leading to an unprecedented heterocyclic template.
Keywords :
Spiropiperidine , Spirofuran , spirocycle , C , O-dianion
Journal title :
Tetrahedron
Journal title :
Tetrahedron