(alpha)-Lithiated Aryloxiranes: Useful Reactive Intermediates

This account focuses on the generation of (alpha)-lithiated aryloxiranes such as lithiated oxazolinylaryloxiranes, lithiated styrene-, phenylpropylene- and stilbene oxides, their chemical and configurational stability, reactivity and some synthetic applications. It is shown how these special reagents have been successfully employed for the preparation of a variety of substances including polysubstituted aryloxiranes, highly strained heterocyclic compounds, (alpha),(beta)-epoxy-(gamma)butyrolactones, cyclopropane carboxylates.