Title of article :
Enantiospecific Total Synthesis of TAN1251C and TAN1251D
Author/Authors :
Mizutani، Hirotake نويسنده , , Honda، Toshio نويسنده , , Takayama، Jun نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
An enantiospecific total synthesis of TAN1251C and TAN1251D has been achieved. An aromatic oxidation reaction of a secondary amine, which is prepared from two molecules of l-tyrosine derivatives, with hypervalent iodine reagent gave a spiro cyclic product as a key intermediate for the synthesis of TAN1251C and D.
Keywords :
TAN1251 alkaloid , total synthesis , aromatic oxidations , hypervalent iodine , spiro cyclization
