Title of article
ortho-Induced transition-metal-free C-arylation cyclization reaction for the synthesis of polysubstituted isocoumarins
Author/Authors
Lei Liu، نويسنده , , Jie Hu، نويسنده , , Xiang-Chuan Wang، نويسنده , , Mei-Jin Zhong، نويسنده , , Xue-Yuan Liu، نويسنده , , Shang-Dong Yang، نويسنده , , Yong-Min Liang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
5
From page
5391
To page
5395
Abstract
A new protocol for the synthesis of polysubstituted isocoumarins from 2-iodobenzoic acid and β-diketone compounds has been developed. The occurrence of C-arylation cyclization reaction in transition-metal-free systems and ortho-induced substrates has been exploited. Reactions using these inexpensive conditions have displayed high functional group tolerance and excellent yields.
Keywords
aryl halides , Transition-metal-free , C-Arylation , ortho-Induced , isocoumarins
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104650
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