Title of article
Rh/chiral sulfinylphosphine catalyzed asymmetric 1,4-addition of arylboronic acids to chalcones
Author/Authors
Guihua Chen، نويسنده , , Junwei Xing، نويسنده , , Peng Cao، نويسنده , , Yan-Jian Liao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
4
From page
5908
To page
5911
Abstract
A general method to obtain enantioenriched 1,3,3-triarylpropan-1-ones bearing a diarylmethine stereocenter was developed using Rh/chiral sulfinylphosphine catalyzed 1,4-addition of arylboronic acids to chalcones. The catalysis progressed smoothly in the presence of 2 mol % catalyst formed in situ from [Rh(C2H4)2Cl]2 and chiral tert-butanesulfinylphosphine and gave the adducts with up to 99% yield and 98% ee.
Keywords
Chiral sulfinylphosphine , Chalcones , 1 , 4-addition
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104712
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