Title of article :
Asymmetric Synthesis of Dihydrofurans via Rh(II)-Catalyzed Cyclopropanation-Rearrangement of Enol Ethers with 1-(Silanyloxy)vinyl Diazoacetates
Author/Authors :
Bernardinelli، Gerald نويسنده , , Muller، Paul نويسنده , , Allenbach، Yves F. نويسنده , , Ferri، Maria نويسنده , , Grass، Stephane نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
The cyclopropanation of dihydrofuran and dihydropyran with methyl 1-(silanyloxy)vinyl diazoacetates in the presence of chiral Rh(II)-catalysts affords cyclopropanes with high diastereo- and enantioselectivitiy. The cyclopropanes, in turn, rearrange to dihydrofurans upon desilylation with TBAF.
Keywords :
Transition metals , Diazo compounds , Stereoselectivity , catalysis , Carbenes
