Author/Authors :
Claudia Lohre، نويسنده , , Corinna Nimphius، نويسنده , , Marc Steinmetz، نويسنده , , Sebastian Würtz، نويسنده , , Roland Fr?hlich، نويسنده , , Constantin G. Daniliuc، نويسنده , , Stefan Grimme، نويسنده , , Frank Glorius، نويسنده ,
Abstract :
Herein we provide an overview on the unique properties of the sterically demanding IBiox-[(−)-menthyl]∙HOTf ligand (such as flexibility and sterics) and an application of this ligand in Pd-catalyzed asymmetric intra- and intermolecular α-arylation reactions. Furthermore we demonstrate the synthesis of novel NHC–metal complexes and a new bifunctional NHC ligand whilst insight into the mechanistic mode of action of IBiox-[(−)-menthyl]∙HOTf in catalysis is provided.
Keywords :
Theoretical calculations , N-heterocyclic carbenes , Conformation studies , Asymmetric catalysis , palladium complex
