Title of article
Zinc-mediated enantioselective addition of terminal 1,3-diynes to N-arylimines of trifluoropyruvates
Author/Authors
Fa-Guang Zhang، نويسنده , , Jia Hai Ma and Bin Wang ، نويسنده , , Yan Zheng، نويسنده , , Jun-An Ma، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
7
From page
7663
To page
7669
Abstract
A facile and effective enantioselective addition of terminal 1,3-diynes to acyclic α-CF3 ketimine esters has been developed by using zinc/Binol complexes. The reaction works well with a variety of aromatic-, aliphatic- and silyl-substituted diynes, providing the desired products in up to 97% yield and 97% enantiomeric excess.
Keywords
Diynylation , Propargylamines , Enantioselectivity , Addition , ketimines
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104911
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