Title of article :
Abiestetranes A and B, two unique tetraterpenes from Abies fabri
Author/Authors :
Yong-Li Li، نويسنده , , Shou-De Zhang، نويسنده , , Hui-Zi Jin، نويسنده , , Jun-Mian Tian، نويسنده , , Yun-Heng Shen، نويسنده , , Xian-Wen Yang، نويسنده , , Honglin Li، نويسنده , , Wei-Dong Zhang، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
Abiestetranes A (1) and B (2), two unique tetraterpenes formed by Diels–Alder cycloaddition between a lanostane triterpenoid and a monoterpenoid, were isolated from Abies fabri. Their structures were elucidated by extensive analysis of NMR data. The electronic circular dichroism was utilized to assign the absolute configuration of 1. Compounds 1 and 2 showed significant cytotoxic activities against ZR-75-30 tumor cell with IC50 values of 6.26 and 1.63 μg/mL, respectively.
Keywords :
Abies fabri , Diels–Alder cycloaddition , Pinaceae , Tetraterpenes , Cytotoxicity , Abiestetranes A and B
Journal title :
Tetrahedron
Journal title :
Tetrahedron
