Title of article :
Preparation of 2,7-Diamino-1,8-naphthyridine: A Useful Building Block for Supramolecular Chemistry
Author/Authors :
Park، Taiho نويسنده , , Mayer، Michael F. نويسنده , , Nakashima، Shoji نويسنده , , Zimmerman، Steven C. نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
A two-step conversion of 2-chloro-7-amido-1,8-naphthyridine to 2,7-diamino-1,8-naphthyridine is described. The process, which involves a nucleophilic aromatic substitution reaction with 4-methoxybenzylamine and subsequent deprotection, can be carried out on a large scale.
Keywords :
amine protecting group , Hydrogen bond , Heterocycles , Nucleophilic aromatic substitution , supramolecular systems
