Title of article
Bioactive polyketides from the sea fan-derived fungus Penicillium citrinum PSU-F51
Author/Authors
Nanthaphong Khamthong، نويسنده , , Vatcharin Rukachaisirikul، نويسنده , , Souwalak Phongpaichit، نويسنده , , Sita Preedanon، نويسنده , , Jariya Sakayaroj، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
6
From page
8245
To page
8250
Abstract
Five new polyketides including two benzopyranones (1 and 2), one isochroman (3) and two anthraquinone-citrinin derivatives (4 and 5) were isolated from the sea fan-derived fungus Penicillium citrinum PSU-F51 together with thirteen known compounds. The structures were determined by spectroscopic methods. The anthraquinone-citrinin derivatives are rare natural products. Compound 4 displayed moderate antibacterial activity against both Staphylococcus aureus and methicillin-resistant S. aureus with equal MIC values of 16 μg/mL, while the known coniochaetone A displayed moderate antifungal activity against Candida albicans with MIC value of 16 μg/mL.
Keywords
Penicillium citrinum , Antibacterial activity , Antifungal activity , Anthraquinone–citrinin derivatives
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1104978
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